Postnatal exposure to low-dose bisphenol A influences various emotional conditions
نویسندگان
چکیده
منابع مشابه
Low-Dose Exposure to Bisphenol A in Early Life
Bisphenol A (BPA) has lower estrogenic potency than 17b-estadiol. The reference dose of BPA is defined as 50 ug/kg bw/day by the Environmental Protection Agency. The lower doses of BPA than no observable effect level are considered safe. However, early life exposure to low-dose BPA may increase the risk of developing adult onset disease. The harmful effects caused by low-dose BPA in fetus and n...
متن کاملEffects of prenatal and postnatal exposure to a low dose of bisphenol A on behavior and memory in rats.
Endocrine disruptors (EDs) are increasingly common chemicals in the environment. Bisphenol A (BPA), used to manufacture polycarbonate plastics, is an ED recognized for its estrogenic, anti-estrogenic, and anti-androgenic effects. Behavior is considered a vital characteristic for an animal's life cycle. This study evaluated the effect of exposure to low doses of BPA during pregnancy and/or lacta...
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Bisphenol-A (BPA) is a monomer used in the production of polycarbonate plastics, epoxies and resins and is present in many common household objects ranging from water bottles, can linings, baby bottles, and dental resins. BPA exposure has been linked to numerous negative health effects throughout the body, although the mechanisms of BPA action on the developing brain are still poorly understood...
متن کاملLow-dose exposure to bisphenol A and replacement bisphenol S induces precocious hypothalamic neurogenesis in embryonic zebrafish.
Bisphenol A (BPA), a ubiquitous endocrine disruptor that is present in many household products, has been linked to obesity, cancer, and, most relevant here, childhood neurological disorders such as anxiety and hyperactivity. However, how BPA exposure translates into these neurodevelopmental disorders remains poorly understood. Here, we used zebrafish to link BPA mechanistically to disease etiol...
متن کاملGestational Exposure to Low Dose Bisphenol A Alters Social Behavior in Juvenile Mice
Bisphenol A (BPA) is a man-made compound used to make polycarbonate plastics and epoxy resins; public health concerns have been fueled by findings that BPA exposure can reduce sex differences in brain and some behaviors. We asked if a low BPA dose, within the range measured in humans, ingested during pregnancy, would affect social behaviors in prepubertal mice. We noted sex differences in socia...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 2013
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.38.539